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We assessed whether minimally invasive catheter evacuation followed by thrombolysis (mistie), with the aim of decreasing clot size to 15 ml or less, would improve functional outcome in patients with intracerebral haemorrhage We assessed whether minimally invasive catheter evacuation followed by thrombolysis (mistie), with the aim of decreasing clot size to 15 ml or less, would improve functional outcome in patients with intracerebral haemorrhage. The mistie iii trial assessed whether minimally invasive catheter evacuation of intracerebral hemorrhage (ich) followed by alteplase instillation improved functional outcomes compared to standard medical care.

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Hanley et al., assessed whether minimally invasive catheter evacuation followed by thrombolysis (mistie), with the aim of decreasing clot size to 15 ml or less, would improve functional outcome in patients with intracerebral haemorrhage. The mistie iii trial, conducted at 78 sites in north america, europe, australia, and asia, was designed to provide a more definitive evaluation of the approach.